Effect of Borneol on ICAM-1 Expression in Retina of Ischemia-reperfusion Rat Model
- VernacularTitle:冰片对大鼠缺血再灌注模型视网膜单链糖蛋白ICAM-1表达的影响
- Author:
Wei ZHAO
;
Ningsheng WANG
;
Suiqing MI
- Publication Type:Journal Article
- Keywords:
Borneol;
Ischemia-reperfusion;
Retina;
ICAM-1
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of borneol administered by gastric gavage or external application on ICAM-1 expression in rat retina with ischemia-reperfusion injury.Methods Rat ischemia-reperfusion model was established.Laser microscope and biological analysis microsoft were used to observe the change of ICAM-1 expression in retina or rats after gastric gavage or external application of borneol.Results Borneol administered by gastric gavage or external application obviously decreased the expression of ICAM-1 after the modeling for 24 hours,the difference being significant as compared with that in the model group(P