Determination of Gentiopicroside in Radix Gentianae Macrophyllae Produced in Gansu Province by HPLC
- VernacularTitle:甘肃产秦艽类药材中龙胆苦苷的含量测定
- Author:
Xiao MA
;
Junru ZHU
;
Luren HE
;
Jianbang ZHAO
- Publication Type:Journal Article
- Keywords:
Radix gentianae macrophyllae;
Gentiopicroside;
HPLC
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
2000;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To determine the content of gentiopicroside and to evaluate the quality of Radix Gentianae Macrophyllae in Gansu province.Methods The HPLC method was performed on Waters C18 column.Methanol-water(3 ∶7) were used as the mobile phase,the flow rate was at 1.0 mL?min-1 with the detection wavelength being 254 nm.Results For gentiopicroside,the linear range was 1.7352～17.3520 ?g and the average recovery was 97.06 %with RSD=2.5 %.Conclusion The content of gentiopicroside in all of the samples produced in Gansu province is higher than or approach to the standard for Radix Gentianae Macrophyllae in Chinese Pharmacopoeia.
