Study on the Inclusion of Volatile Oil Extracted from Rhizoma Chuanxiong and Radix et Rhizoma Asari with ?-Cyclodextrin
- VernacularTitle:?-环糊精包合川芎和细辛挥发油的正交试验研究
- Author:
Qiyun MU
;
Xinmin RUAN
- Publication Type:Journal Article
- Keywords:
RHIZOMA CHUANXIONG/production & preparation;
RADIX ET RHIZOMA ASARI/production & preparation;
ORTHOGONAL DESIGN;
?-CYCLODEXTRIN
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the process conditions for ?-cyclodextrin-inclusion of volatile oil obtained from Rhizoma Chuanxiong and Radix et Rhizoma Asari in Guanxin Zhitong Cataplasma,which is prescribed by Professor Deng Tietao.Methods The orthogonal design was used for the optimization of inclusion conditions.With the transformation rate of the volatile oil in inclusion complex and with the yield of inclusion complex as the evaluation indexes,the mass ratio of ?-cyclodextrin to oil,the temperature and the inclusion time were used as the main factors of L9(34)orthogonal design.Results The optimal conditions for inclusion were as follows: the mass ratio of ?-cyclodextrin to oil being 8∶1,in a saturated water solution,inclusion temperature at 60 ℃,and stirring for 1h.Conclusion The optimal conditions for ?-cyclodextrin-inclusion of volatile oil from Rhizoma Chuanxiong and Radix et Rhizoma Asari are steady and feasible.
