Effect of Qianlieantong Tablets on NE-induced Contraction of Rabbit Trigone Muscle
- VernacularTitle:前列安通片对去甲肾上腺素诱导家兔离体膀胱三角肌收缩的影响
- Author:
Lu HU
;
Peihai ZHANG
- Publication Type:Journal Article
- Keywords:
Qianlieantong tablets;
spasmolysis;
bengin prostatic hyperplasia;
rabbit
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe spasmolytic effect of Qianlieantong tablets. Methods Twelve rabbits were randomly divided into 2 groups. One group was to prepare ring muscles, another was to prepare longitudinal muscles. Contraction of trigone muscle was induced by NE. Effects of 6 groups drug were observed, which were high, middle and low concentration Qianlieantong group, Hytrine group, blank group, Tween 80 group (TW-80). Results Qianlieantong tablets can significantly inhibit contraction of NE-inducted rabbit trigone muscle (including ring and longitudinal muscles) in vitro, and the inhibition was positively correlated with concentration, which was less than Hytrine. Conclusions Qianlieantong tablets had spasmolytic effect of alleviating BPH-induced badder outlet obstruction and reducing dynamic factors caused by BPH.
