Quality standard for Yiganjian Tablets
- VernacularTitle:乙肝健片质量标准研究
- Author:
Yarong LIU
- Publication Type:Journal Article
- Keywords:
Yiganjian Tablets;
TLC;
Herba Halenia;
extract of Radix et Rhizoma Glycyrrhizal;
Radix Astragali;
1-hydroxy-3,7,8-trimethoxyxanthon;
monoammonium glycyrrhizinate;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To establish the methods of identifing and determining Yiganjian Tables. METHODS: Herba Halenia,extract of Radix et Rhizoma Glycyrrhizale,Radix Astragali were identified by TLC.The content of 1-hydroxy-3,4,5-trimethoxyxanthon in Herba Halenia was determined by HPLC on Hypersil-ODS2 column with the mobile phase of methanol-0.2%H_3PO_4(55∶45).The detective wavelength was set at 243 nm and monoammonium glycyrrhizinate was determinad by HPLC on Hypersil-ODS2 column with the mobile phase of acetonitrile-2% aceacid(60∶40).The detective wavelength was set at 250 nm. RESULTS: The linear range of 1-hydroxy-3,4,5-trimethoxyxanthon was from 0.173 2 to 0.866 0 ?g.The average recovery was 100.56%,RSD was 2.7%(n=9).The linear range of monoammonium glycyrrhizinate was from 0.55 to 2.75 ?g.The average recovery was 98.29%,RSD was 1.7%(n=9). CONCLUSION: The method is simple,accurate and sensitive,so it can be used for the quality control of Yiganjian Tablets.
