Apparent partition coefficient of Hawthorn leaf flavonoids in phospholipids complex
- VernacularTitle:山楂叶总黄酮中不同极性成分磷脂复合物的表观油水分配系数研究
- Author:
Yang XIONG
- Publication Type:Journal Article
- Keywords:
Hawthorn leaf;
flavonoids;
phospholipid complex;
rhamnosylvitexin;
rutin;
quercetin;
apparent partition coefficient
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To explore the appearent partition coefficient of flavonoids from Hawthorn leaf in phospholids complex. METHODS: With the aid of the shake-flask method,The contents of rhamnosylvitexin,rutin and quercetin were determined by HPLC and apparent partition coefficient in the system of n-octyl alcohol and water of each ingredient in the physical mixture of Hawthorn leaf flavonoids and phospholipids,Hawthorn leaf flavonoids and its phospholipids complex were calculated respectively. RESULTS: Apparent partition coefficient of rhamnosylvitexin and rutin and quercetin in phospholipids complex were enhanced comparing with both in Hawthorn leaf flavonoids and the physical mixture of Hawthorn leaf flavonoids and phospholipids. CONCLUSION: Phospholipid complex may be an effective carrier to elevate the oral bioavailability of total flavonoids from effective fraction of Hawthorn leaf.
