Antitumoral activity of Zhongjiefeng Injection and its influence on the cell cycle of gastric cancer SGC-7901
- VernacularTitle:肿节风注射液抗肿瘤实验及对人胃癌SGC-7901细胞周期的影响
- Author:
Yi ZHAO
;
Youzhi SUN
;
Binghua XIAO
;
Qi CHEN
- Publication Type:Journal Article
- Keywords:
Zhongjiefen(ZJF);
H22 tumor;
gastric cancer SGC-7901;
cell cycle
- From:
Chinese Traditional Patent Medicine
1992;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To study the effect of Zhongjiefeng Injection(Herba sarcandrae) on mouse liver cancer H_22,and its activities on gastric cancer SGC-7901 in vitro,to find out its influence on the cell cycle. METHODS: By injecting H_22 tumor cells in vivo into mice to check its inhabition on entity and ascites tumor.MTT colorimetric method was used to study the anti-tumor activity on gastric cancer SGC-7901,then we calculated its IC_50 and applied the flow cytometry(FCM) to detect its influence of cell cycle. RESULTS: The rates of inhabition on H_22 entity tumor with three concentrations were 29.8%,36.2%,40.5%,and was the remarkable different from the model group(P
