Study on Purification of Swertiaman from Swertia pesudochinensis Hara. with Macroporous Adsorbent Resin
- VernacularTitle:大孔吸附树脂纯化当药中獐牙菜苦苷的研究
- Author:
Dacheng ZHOU
;
He MENG
;
Rongsheng LI
- Publication Type:Journal Article
- Keywords:
Swertia pesudochinensis Hara.;
iridoid glycosides;
swertiaman;
macroporous adsorbent resin;
HPD-100
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the suitable type of macroporous adsorbent resin to purity swertiaman from Swertia pesudochinensis Hara., and determine the parameters and conditions for its purification procedures. Method Purification effect of 8 types of macroporous resins used to purify the Swertia pesudochinensis Hara. were inspected, with the content of swertiaman as index. Result HPD-100 type resin showed better effect than others, it had optimum adsorption and elution parameters with its dynamic saturated adsorption ratio was 70.48 mg/g. After eluted with 2 BV of distilled water, 4 BV 30% ethanol and collected, the content of swertiaman in the spray dried powder was 52.29%. Conclusion HPD-100 types macroporous resin showed a better comprehensive adsorption property and can be used to enrich and purify the swertiaman included active fraction of iridoid glycosides for industrialization.
