Effect of Qingfei Oral Liquid on Transforming Growth Factor-?_1 and Platelet-Derived Growth Factor-BB mRNA Gene Expression of Human Embryonic Lung Fibroblast Cells Infected by Adenovirus Type 3I and 7b
- VernacularTitle:清肺口服液对3I、7b型腺病毒感染人胚肺成纤维细胞TGF-?_1、PDGF-BB mRNA基因表达的影响
- Author:
Wenge WANG
;
Siwen CHEN
;
Shouchuan WANG
- Publication Type:Journal Article
- Keywords:
Qingfei oral liquid;
human embryonic lung fibroblast cells;
adenovirus;
TGF-?1;
PDGF-BB mRNA;
drug contained serum
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effect of Qingfei oral liquid contained serum on the transforming growth factor-?1 (TGF-?1) and platelet-derived growth factor-BB (PDGF-BB) mRNA gene expression of human embryonic lung fibroblast cells infected by adenovirus (ADV) type 3I and 7b. Method TGF-?1 and PDGF-BB mRNA expression of human embryonic lung fibroblast cells infected by ADV type 3I and 7b were determined by in situ hybridization before and after treated with Qingfei oral liquid contained serum. Results ADV could up-regulate TGF-?1 and PDGF-BB mRNA of human embryonic lung fibroblast cells (P