Therapeutic Effect of Jade Maid Decoction for Experimental Periodontitis in Rabbits
- VernacularTitle:玉女煎对实验性兔牙周炎模型的治疗作用
- Author:
Yi LI
;
Yanhui LIU
;
Gailing WANG
;
Ludi FU
- Publication Type:Journal Article
- Keywords:
PERIODONTITIS/TCM-WM therapy;
JADE MAID DECOCTION/pharmacology;
TOOTH/pathology;
DISEASE MODELS,ANIMAL;
RABBITS
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the therapeutic effect of Jade Maid Decoction(JMD),a Chinese herbal prescription for nourishing yin and clearing stomach-heat,on experimental periodontitis.Methods Twenty-four New Zealand rabbits were randomized into the model group,JMD group(oral use of JMD 23 g?kg-1?d-1),external application group(periodontal injection of minocycline hydrochloride ointment 50mg),and the combination group(oral use of JMD and periodontal injection of minocycline hydrochloride ointment).Experimental periodontitis was induced by ligation method.The treatment lasted 6 weeks.Gingival bleeding on probing(BOP) and probing pocket depth(PPD) were detected each week after medication,and pathological examination of the mandible was used to confirm the therapeutic effect after treatment.Results Gingival BOP was reduced to various degrees at different time in the three medication groups,and the effect was obvious in the combination group;PPD was also decreased to various degrees,and the difference of PPD between the three medication groups and the model group was significant after treatment for 4 weeks(P
