Mechanism and Evaluation Methods of Allergy Caused by Traditional Chinese Medicine Injection
- VernacularTitle:中药注射液引起过敏的机制及评价方法
- Author:
Lian ZHOU
;
Xia LUO
;
Qing WANG
- Publication Type:Journal Article
- Keywords:
Traditional Chinese medicine injection;
Allergy;
Good Laboratory practice(GLP);
Evaluation
- From:
Chinese Journal of Pharmacoepidemiology
2007;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To summarize the allergic mechanism caused by traditional Chinese medicine injection (TCMI) to provide some references for perfecting Good Laboratory Practice(GLP) of TCMI.Method:The related iteratures in data bases at home and abroad were reviewed,and the present experimental research methods about allergies were referred to to have a view of future studies.Result:The allergic mechanism of TCMI was mostly antigen-antibody reaction, part of which was anaphylactoid reaction.The method of the evaluation of allergy caused by TCMI only was animal experiments, but there were still some allergies caused by TCMI after the evaluation with this method.The present experimental research methods indicated that the detection of mediators of inflammation and FCM(Flow Cytometry) could be used to evaluate the allergies caused by TCMI.Conclusion:More attention should be paid to allergies caused by TCMI for its complicated mechanism and frequent occurrences in clinic.It may be an effective way to evaluate the allergies caused by TCMI with several methods including in vivo and in vitro.
