A Case of Renal Infarction associated with Protein C and S Deficiency.
- Author:
Chang Dong YEO
1
;
Hui Jeong HWANG
;
Sung Min PARK
;
Sang Won SON
;
Seok Joon SHIN
;
Ho Cheol SONG
;
Euy Jin CHOI
;
Yoon Sik CHANG
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. drsong@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Infarction;
Protein C;
Protein S deficiency
- MeSH:
Adult;
Angiography;
Atherosclerosis;
Atrial Fibrillation;
Flank Pain;
Heart Valve Diseases;
Heparin;
Humans;
Infarction*;
Male;
Protein C Deficiency;
Protein C*;
Protein S;
Protein S Deficiency;
Pulmonary Embolism;
Renal Artery;
Renal Artery Obstruction;
Stroke;
Thromboembolism;
Vasculitis;
Venous Thrombosis;
Warfarin
- From:Korean Journal of Nephrology
2006;25(3):457-460
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Renal infarction usually occurs in patients with atrial fibrillation, valvular heart disease, trauma, renal artery stenosis, atherosclerosis, vasculitis, and hypercoagulable state. Protein C or S deficiency is an uncommon condition among hypercoagulable states and manifests deep vein thrombosis, pulmonary thromboembolism, cerebrovascular accident. In this report, we present a case of renal infarction occurred in 36-year-old male without underlying diseases except a family history of thromboembolism. He was admitted to our hospital due to an abrupt and continuous left flank pain. He had no previous history of an arterial or venous thrombosis. Tomography and renal angiography showed a left renal artery occlusion. He was treated with heparin and warfarin therapy. In laboratory tests, Protein C antigen level and protein S activity was 51.80% (72-160%) and 48% (65-140%). Thus, we concluded that renal infarction was secondary to combined type 1 protein C deficiency and type 2 protein S deficiency.
