Advanced Researches on Cell Adhesion Molecules of Immune System under Microgravity
- VernacularTitle:微重力条件下免疫系统相关黏附分子的研究进展
- Author:
Yu ZHANG
;
Chen SANG
;
Fengyuan ZHUANG
- Publication Type:Journal Article
- Keywords:
microgravity;
immune system;
cell adhesion molecules(CAMs);
signal transduction
- From:Space Medicine & Medical Engineering
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Returning astronauts had experienced decreased immune function and increased vulnerability to infection during spaceflights.In immune system,cell adhesion molecules(CAMs) play an important role in regulating immune response in normal physiological conditions.Studying changes of CAMs under microgravity could not only understand the effects of microgravity and its molecular mechanism on immune function,but also help to study the relative mechanism about cell sensation of microgravity.In this review,we will introduce some downstream signal pathways,gene expression and the effects on cell functions under microgravity.All of them are regulated by cell adhesion molecules related with the immune system.
