Intra-subject Image Registration between Expiration and Inspiration Lung Volumes of High Resolution CT
- VernacularTitle:同体呼气相和吸气相肺部高分辨率CT体积图像的配准
- Author:
Yingyue ZHOU
;
Huanqing FENG
;
Chuanfu LI
- Publication Type:Journal Article
- Keywords:
high resolution CT;
intra-subject image registration;
affine transformation;
non-rigid registration;
lung
- From:Space Medicine & Medical Engineering
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To register two breath-hold lung volumes image from one subject with deep expiration and deep inspiration.Methods Three pairs of thoracic high resolution CT serial from three subjects were collected under two breath-hold respiration stages.The lung parenchyma of every serial was segmented using the serial segmentation algorithm.Left and right lungs were stored separately.Expiration and inspiration volume images of single lung were registered.Firstly,affine transformation parameters were found based on the anatomic flag surfaces and expiration image volume was re-sampled with affine transformation.Secondly,"Demons" algorithm was employed to register two image volumes non-rigidly.Results Two lung surfaces and the inner structures have a nice registration.The average volume overlap of two images before registration is 0.7982.After global affine transformation,it improves to 0.8936.After "Demons",it is up to 0.9544.The average descending percentage of root mean square errors is 19.83%(after the global affine transformation) and 49.43%(after the "Demons" non-rigid registration).Conclusion The intra-subject registration between two lung image volumes with large deformations described here has an effective registration result.It offers a good base to analyze the lung respiration function.
