Effects of Tongxin Plaster on Serum Macrophage Colony Stimulating Factor, Homocysteine and Granules Membrane Protein-140 in Patients with Coronary Heart Disease
- VernacularTitle:通心贴对冠心病心绞痛患者血清M-CSF、HCY、GMP-140的影响
- Author:
Jianming YIN
;
Luyi LUO
;
Dachuang ZHANG
- Publication Type:Journal Article
- Keywords:
angina pectoris;
coronary heart disease;
Tongxin Plaster;
macrophage colony stimulating factor;
homocysteine;
granules membrane protein-140
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Tongxin Plaster on serum macrophage colony stimulating factor (M-CSF), homocysteine (HCY), and granules membrane protein-140 (GMP-140) of patients with angina pectoris of coronary heart disease. Methods Eighty CHD patients were randomly divided into two groups. Forty-one cases in treatment group were given acupoint application of Tongxin Plaster on acupoint Tanzhong (CV 17) and Xinshu (BL 15) 12 hours a day. Thirty-nine cases in control group were given orally Shexiangbaoxin Pill, 2 pills twice a day. The treatment course of the two groups was 3 weeks. The serum levels of M-CSF, HCY and GMP-140 were detected respectively. Results After treatment, the levels of M-CSF, HCY, GMP-140 in both groups were all decreased significantly (P 0.05). Conclusion Tongxin Plaster has good effects on antagonizing inflammatory response of coronary artery, inhibiting activation of platelets and degrading the level of homocysteine, which may be one of the mechanisms for Tongxin Plaster in treating CHD.
