A Case of Primary Sjogren's Syndrome associated with Minimal Change Nephrotic Syndrome Concurrently Manifested with Sicca Complex.
- Author:
Hyo Jeong OH
1
;
Yu Min LEE
;
Hyun Jun JU
;
Sung Won JUNG
;
Kang Won LEE
;
Hyeok SHIM
;
Myeung Su LEE
;
Jin Ho SHIN
;
Seon Ho AHN
;
Ju Hung SONG
Author Information
1. Department of Internal Medicine, Wonkwang University School of Medicine, Iksan, Korea. ashneph@wmc.wonkwang.ac.kr
- Publication Type:Case Report
- Keywords:
Glomerulonephritis;
Minimal change disease;
Nephrotic syndrome;
Sjogren's syndrome
- MeSH:
Antigen-Antibody Complex;
Autoimmune Diseases;
Glomerulonephritis;
Glomerulonephritis, Membranoproliferative;
Humans;
Kidney;
Korea;
Lacrimal Apparatus;
Liver;
Lung;
Mouth;
Nephritis, Interstitial;
Nephrosis, Lipoid*;
Nephrotic Syndrome;
Rheumatic Diseases;
Salivary Glands;
Sjogren's Syndrome*
- From:Korean Journal of Nephrology
2006;25(3):473-478
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sjogren's syndrome is an autoimmune disease causing eye or dry mouth from the lymphocytic infiltration in the lacrimal gland and the salivary gland, and is classified as primary or secondary based on the absence or presence of complicating systemic rheumatic diseases. Extraglandular systemic lesions involving organs such as the lungs, liver, and kidney are seen, and renal involvement of these is reported to occur in 20% to 50% of patients with primary Sjogren's syndrome, and most commonly manifested with a tubulointerstitial nephritis. But a little over 20 cases with glomerulonephritis have been reported in the literature review, and only one case was reported in Korea. Glomerulonephritis is a late sequelae in the course of the disease, and is most attributed to deposition of immune complexes. Membranoproliferative glomerulonephritis are the most common glomerular lesions and only one case of minimal change nephrotic syndrome was reported in the literature review, and no previous case was reported in Korea. We report a minimal change nephrotic syndrome that is concurrently manifested with sicca complex in a case of Sjogren's syndrome.
