Therapeutic effect of transcatheter arterial chemoembolization combined with radiofrequency ablation or ~(125)I interstitial brachytherapy on primary hepatocellular carcinoma:a comparative study
- VernacularTitle:肝动脉化疗栓塞联合射频消融或放射性粒子组织间放疗对原发性肝癌的疗效比较研究
- Author:
Miao YU
;
Jiakai LI
;
Hao YIN
;
Yueyong XIAO
;
Jinshan ZHANG
- Publication Type:Journal Article
- Keywords:
hepatocellular carcinoma;
transcatheter arterial chemoembolization;
radiofrequency ablation;
125I seed
- From:
Journal of Interventional Radiology
2001;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the effectiveness of transcatheter arterial chemoembolization(TACE) combined with radiofrequency ablation(RFA) and TACE combined with 125I interstitial brachytherapy in the treatment of primary hepatocellular carcinoma(HCC) and to compare the results of the two therapies.Methods Fifty patients with HCC underwent TACE and RFA during laparotomy and 34 patients received TACE and radioactive 125I particle seeding.Four weeks after the procedure,dynamic enhanced CT or MR scanning was performed for a check.If the lipiodol deposit was poor,TACE was repeated.Follow-up check was made at regular intervals to observe the results.Results One month after the treatment,the local control rate of the tumor for TACE +RFA and TACE + 125I particle seeding combination therapy was 98.0% and 97.1%,respectively.No statistically significant difference existed between the two therapies.Conclusions Both TACE combined with RFA or with 125I particle seeding are effective therapies for HCC,which can be regarded as an ideal alternative therapy for patients who have failed to respond to TACE alone.
