Antiinflammatory and Bacteriostasis Pharmacodynamics Effects Research of Sanxiaoyuchuang Ointment
- VernacularTitle:三效愈创软膏抗炎抑菌药效学研究
- Author:
Jie ZHANG
;
Nan ZHANG
;
Haitao GE
- Publication Type:Journal Article
- Keywords:
Sanxiaoyuchuang ointment;
anti-inflammatory and bacteriostasis;
animal model;
clearing away heat and toxic material
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2008;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effects of Sanxiaoyuchuang ointment on the mice inflammatory model induced by Dimethylbenzene,bacteria strains in vitro and mice pneumococcus pneumonia model.Methods Mice inflammatory model induced by Dimethylbenzene,in vitro bacteria strains model and mice pneumococcus pneumonia model were founded respectively,randomed and controlled methods were used,exposed to different dosages of Sanxiaoyuchuang ointment,the changes of auricle swelling degree,earcapillary vessel permeability,the growth rate of strains and pneumococcus pneumonia mice's mortality were measured.Results 8% dose Sanxiaoyuchuang group had obvious inhibition effects on mice auricle swelling induced by Dimethylbenzene,it had no obvious difference compared with Jingwanhong group.It could also lower the mice earcapillary vessel permeability,inhibit or eradicate the colon bacillus,Staphylococcus aureus,cyanomycosis,Sonne dysetery,typhoid bacillus,and decrease the mortality rate of mice intraperitoneal injected by pneumococcus.Conclusion Sanxiaoyuchuang ointment has good antiinflammatory and bacteriostasis(in vivo and in vitro) pharmacodynamics effects.