Clinical study of hepatoarterical catheter chemotherapy for gastric carcinoma with liver metastasis

VernacularTitle:胃癌肝转移术后肝动脉灌注化疗临床观察
Author: Qiangsheng Lü ; Yadong WANG ; Hui CHENG ; Feng LU ; Yuandong GAO
Publication Type:Journal Article
Keywords: Stomach neoplasms; Neoplasm metastasis; Chemotherapy; cancer; regional
From: Cancer Research and Clinic 2009;21(12):813-814,817
CountryChina
Language:Chinese
Abstract: Objective To study the effect and value of hepatoarterical catheter chemotherapy in treating gastric carcinoma with liver metastasis. Methods A total of 31 cases of gastric carcinoma with liver metastasis undergoing radical operation were preoperatively randomly divided into 2 groups: Regional infusion chemotherapy (treatment group, 17 cases) and peripheral venous chemotherapy (control group, 14 cases). Results The short-term effectiveness of the treatment group was 88.3 %(15/17). The survival rates of 1, 2, 3 year were 88.2 %, 62.7 %, 28.9 %, respectively. However, the short-term effectiveness of the control group was 28.6 %(4/14). The survival rates of 1, 2, 3 year were 68.1 %, 38.9 %, 13.0 %, respectively. There was obvious difference between the two groups (χ~2 = 12.87, P <0.05;χ~2 =5.511, P<0.01). Conclusion Hepatoarterical catheter chemotherapy is effective for gastric carcinoma with liver metastasis undergoing radical operation and has less toxic side effects.