Changes of Protein Calbindin-D28k Expression in Hippocampus of Cerebral Ischemic Rats and the Influence of Acupuncture
- VernacularTitle:脑缺血损伤大鼠海马区钙结合蛋白Calbindin-D28k蛋白表达的变化及针刺对其影响
- Author:
Huifang MA
;
Xiujun REN
;
Caixia LIN
;
Ya TU
- Publication Type:Journal Article
- Keywords:
CEREBRAL ISCHEMIA/acup-mox therapy;
BRAIN/pathology;
DISEASE MODELS,ANIMAL;
RATS;
POINT GV20(BAIHUI);
POINT GV26 (SHUIGOU)
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
2001;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of acupuncture on protein Calbindin-D28k expression in hippocampus of rats with cerebral ischemia,and to investigate its influence on rats neurological behavior.Methods Male SD rats were randomized into blank control group,model group and acupuncture group,10 rats in each group.The rat model of focal cerebral ischemia was established by chemical-stimulation-induced occlusion of the unilateral middle cerebral artery.Acupuncture group received acupuncture of acupoints of Baihui and Shuigou,one time per day for 7 days.The changes of protein Calbindin-D28k expression in hippocampus of rats were observed before and after treatment,and the score of rats neurological behavior was observed after the modeling for 1~2 hour(s)and after treatment.Results Calbindin-D28k expression was decreased in the hippocampus of model group(P
