Differential analysis on two-dimensional electrophresis pattern of seminal plasma protein of varicocele patients
- VernacularTitle:双向电泳分析精索静脉曲张不育患者精浆蛋白质的表达差异
- Author:
Jie LI
- Publication Type:Journal Article
- Keywords:
Varicocele;
Proteome;
Two-dimensional gel electrophoresis
- From:
Journal of Chongqing Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To identify differential proteins expression of seminal plasma of varicocele patients and normal person,providing evidence for further exploring the molecular mechanism of infertility caused by varicocele.Methods:The differential proteins expression of seminal plasma of varicocele patients and normal person were characterized by means of two-dimensional gel electrophoresis(2-DE).Results:The well-resolved,reproducible 2-DE seminal plasma were obtained.The 38 differential protein spots were identified.Conclusion:The male infertility might due to the expression and modification of some proteins in seminal plasma of varicocele patient.Further analysis on the different proteins'expression helps revealing molecule mechanism of varicocele causing male infertility.
