Clinical Observation of Low Molecular Weight Heparin in Prevention of Acute Pulmonary Embolism in Patients Following General Surgery
- VernacularTitle:低分子肝素预防普外科术后肺栓塞临床观察
- Author:
Rong LI
;
Zhuoyong QUAN
;
Yingtian ZHANG
- Publication Type:Journal Article
- Keywords:
Pulmonary embolism;
General Surgery Patients;
Prevention;
LMWH
- From:Chinese Journal of Pharmacoepidemiology
2007;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the perioperative anticoagulant therapy for patients in prevention of moderate or high risk of pulmonary embolism(PE)after general surgery.Method:1146 patients who had undergone major general surgery were divided into a non-anticoagulant therapy group and an anticoagulant therapy group.There were 743 patients without the anticoagulant therapy during Jan.2005 to Aug.2008,a preventive anticoagulant therapy was performed on 403 patients who recived 5 000IU(142 patients at moderate risk of PE)or 10 000IU(261 patients at high risk of PE)low molecular weight heparin(LWMH)subcutaneous injection after major general surgery during Jan.2006 to Nov.2008.Result: Five cases died and 2 survived among 7 PE patients.Hemorrhage occurred in 3 out of 403 cases(0.7%),but no PE occurred among 403 patients administered with the LWMH anticoagulant therapy.The incidence of PE in the patients reciving LWMH decreased from 0.9%to 0(P
