Clinical Application of Fritillaria thunbergii Miq. Granule in Refractory Acute Leukemia during Perichemotherapy
- VernacularTitle:浙贝颗粒在难治性白血病围化疗期的临床应用研究
- Author:
Dongyun LI
;
Shaodan TIAN
;
Xinyi CHEN
- Publication Type:Journal Article
- Keywords:
Fritillaria thunbergii Miq. granule;
refractory acute leukemia;
perichemotherapy
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To translate the findings from fundamental research into clinical application and to evaluate the clinical efficiency and safety of Fritillaria thunbergii Miq. granule as adjunctive means of chemotherapy during peri chemotherapy of refractory acute leukemia. Methods Patients in multiple hospitals were randomly divided into two groups with Fritillaria thunbergii Miq. granule treatment or synchronous control at three days before chemotherapy respectively, according to random approaches for medical treatment. The clinical therapeutic effects were then determined after one course of treatment. Results According to the research project, 138 patients were analyzed statistically, 72 in Fritillaria thunbergii Miq. granule group and 66 in control group. The complete remission rate (CR) of Fritillaria thunbergii Miq. granule group and control group were 36.8% and 25.8% respectively, while the total effects were 77.8% and 53.0%, which was significantly different (P
