Determination of Ferulic Acid in Jiegu Capsule by RP-HPLC
- VernacularTitle:反相高效液相色谱法测定接骨胶囊中阿魏酸的含量
- Author:
Jingjuan MENG
;
Fengping SHAN
- Publication Type:Journal Article
- Keywords:
Jiegu Capsule;
Ferulic acid;
HPLC;
content determination
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a method for determination of Ferulic acid in Jiegu Capsule. Method The samples were determined by RP-HPLC on a Hypersil C18 column (4.6 mm?250 mm, 5 ?m). The mobile phase consisted of methanol and 1% acetic acid (33∶67). The detection wavelength was at 320 nm and the flow rate was 1.0 mL/min. Results The calibration curves of Ferulic acid was linear in the range of 6～60 ?g/mL (r =0.999 9). The average recovery was 99.6% and RSD was 1.8%. Conclusion The method is simple and accurate, which can be used for the quality control of Jiegu Capsule.
