Effect of Semen Cassiae extracts on expression of lipogenesis genes in hyperlipidemia model mice
- VernacularTitle:决明子提取物对高血脂模型小鼠聚脂基因表达的影响
- Author:
Shumin LIU
;
Chao SUN
;
Weihua XIE
- Publication Type:Journal Article
- Keywords:
Semen Cassiae;
blood-fat;
adipogenesis genes
- From:
Chinese Traditional and Herbal Drugs
1994;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the effects of Semen Cassiae extract on lipid metabolism of hyperlipidemia model mice.Methods In this experiment,mice were sc injected with two different concentration of Semen Cassiae extract,and sacrificed at 1,2,and 4 h.The blood samples were withdrawn from the eye vein.The plasma biochemical indexes were detected by using the kit,and real time PCR was used to analyze the expression of adipogenesis genes with time series.Results For hyperlipidemia model mice treated with Semen Cassiae extract serum total cholesterol(TC),triglyeride(TG),and low density lipoprotein cholesterol(LDL-C) could be decreased significantly(P
