Establishment of a rat model for orthotopic allograft kidney transplantation
- VernacularTitle:一种大鼠异体肾移植模型的建立
- Author:
Jiabing LI
- Publication Type:Journal Article
- Keywords:
Kidneytransplantion;
Rats;
Model
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish a feasible and stable rat model of kidney transplantation. Methods:SD and Wistar rats were used as the donors and the recipients. with the hellp of extradural catheter,the donor inferior vena was anastomosed end-to-end with the recipient left renal vein. An end-to-side anastomosis of abdominal aorta was operated. The donor ureter with ureterocystic flap was conducted to the recipient’s bladder. Results:A modified rat model of kidney transplantation was successfully established. The average total operation time was(130?20) min. The average time of warm ischemia and cold ischemia was less than 20 s and 50 min respectively. The success rate of operation reached about 90.77%. Conclusion:This feasible model of kidney transplantation is feasible and stable.