Therapeutic Effect of Spleen-strengthening,Lung-clearing and Phlegm-resolving Therapy for Chronic Obstrustive Pulmonary Disease Complicated with Systemic Inflammatory Response Syndrome and Its Influence on Nuclear Factor ?B Expression
- VernacularTitle:健脾清肺化痰法对慢性阻塞性肺疾病合并全身炎症反应综合征疗效及核因子-?B表达的影响
- Author:
Jianbo LIU
;
Haijuan YANG
- Publication Type:Journal Article
- Keywords:
PULMONARY DISEASE,CHRONIC OBSTRUCTIVE/TCM-WM therapy;
SEPSIS SYNDROME/TCM-WM therapy;
NUCLEAR FACTOR ?B/ blood;
CHEN XIA LIUJUNZI DECOCTION/therapeutic use;
WEIJING DECOCTION/therapeutic use
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the therapeutic effect of spleen-strengthening,lung-clearing and phlegm-resolving herbs for the treatment of acute attack of chronic obstrustive pulmonary disease(COPD) complicated with systemic inflammatory response syndrome(SIRS),and to observe their effect on nuclear factor ?B(NF-?B)expression level.Methods Sixty qualified patients differentiated as deficiency of spleen and lung,phlegm-heat accumulating the lung were equally randomized into two groups:the control group received routine western medical treatment including oxygen inhalation,antibiotics and bronchodilator,and the treatment group received Chen Xia Liujunzi Decoction and Weijing Decoction,which have the actions of strengthening spleen,clearing lung,and resolving phlegm,one dose per day,for 7 days.The changes of clinical symptoms and signs,blood gas parameters and NF-?B expression level were observed.Results After treatment,clinical symptoms and signs such as cough,expectoration,dyspnea,shortness of breath,and wheeze were relieved in both groups(P
