Influence of Wind-dispelling Therapy on Therapeutic Effect of Blood-cooling and Kidney-tonifying Herbs for Idiopathic Thrombocytopenic Purpura
- VernacularTitle:祛风法对凉血补肾中药治疗慢性特发性血小板减少性紫癜疗效的影响
- Author:
Mei DAI
;
Zhixiong CHEN
;
Tianqi YU
;
Hongguang YANG
;
Yayong CHEN
- Publication Type:Journal Article
- Keywords:
PURPURA,THROMBOCYTOPENIC/TCD therapy;
DISPELLING WIND;
COOLING BLOOD;
TONIFYING KIDNEY
- From:
Journal of Guangzhou University of Traditional Chinese Medicine
1999;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of wind-dispelling therapy on therapeutic effect of blood-cooling and kidney-tonifying herbs for chronic idiopathic thrombocytopenic purpura(CITP),and to investigate its immunoregulatory effect.Methods Forty-two CITP patients were randomized into 2 groups:the treatment group(N=22) received therapy of dispelling wind,cooling blood and tonifying kidney,and the control group(N=20) received therapy of cooling blood and tonifying kidney.Six weeks constituted one treatment course,and the treatment lasted 3 courses.Serum interleukin 2(IL-2),soluble IL-2 receptor(sIL-2R),Fas protein,Fas-L protein,and platelet-associated immunoglobulin G(PAIgG) levels and lymphocyte subtypes were compared before and after treatment.Results In the treatment group,14 patients were clinically cured,5 markedly effective,2 effective,1 ineffective and the total effective rate was 95.5%;in the control group,8 patients were clinically cured,4 markedly effective,3 effective,5 ineffective and the total effective rate was 75.0%.The therapeutic effect in the treatment group was superior to that in the control group(P
