Expression and clinical significance of Notch1 and Smad4 in colorectal carcinoma
- VernacularTitle:Notch1与Smad4在大肠癌中的表达及其临床意义
- Author:
Bin LIU
- Publication Type:Journal Article
- Keywords:
Notch1;
Smad4;
Colorectalcarcinoma;
Immunohistochemistry
- From:
Journal of Chongqing Medical University
1986;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To observe the expression of Notch1 and Smad4in colorectal carcinoma and their clinical significance. Methods: Immunohistochemistry staining was used to detect the expression of Notch1 and Smad4 in 51cases of colorectal carcinoma. Results:(1) The expression of Notch1 in colorectal carcinoma was higher than that in the normal tissue(P0.05),except histological grading and pathological types of patients(P0.05),except Dukes stage,lymph node of metastasis and pathological types of patients (P
