On-Line quality control of Compound Danshen′s extracting process by NIR
- VernacularTitle:NIR技术对复方丹参提取过程的在线监控研究
- Author:
Yan LIU
;
Yanying ZHANG
;
Jinwei ZHANG
;
Aijun ZHANG
- Publication Type:Journal Article
- Keywords:
Compound Danshen;
NIR technique;
on-line quality control;
HPLC
- From:
Chinese Traditional and Herbal Drugs
1994;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To research and develop a model of the representative active component's content by NIR spectroscopy,so as to realize the on-line quality control of extracting process for multiple herbal medicine system in product scale.Methods The on-line NIR detection of extracting process was used to obtain the NIR spectrum,HPLC detection of the extracts was carried out to determine the content of danshensu,and PLS method was used to establish the relationship between the information of NIR and HPLC.Results The optimum NIR wavelength range was 9 715-7 082 cm-1,R=0.959 4,RMSEC=0.049 4,the average relative error was 7.2%.Conclusion NIR Technique could be used in the on-line quality control of Compound Danshen's extracting process.
