Medicines Composition Optimization of Guizhi Gancao Decoction Extracted by Semi-bionic Extraction
- VernacularTitle:桂枝甘草汤方药半仿生提取法药材组合方式的优选
- Author:
Ping XU
- Publication Type:Journal Article
- Keywords:
Guizhi Gancao Decoction;
semi-bionic extraction;
Glycyrrhetinic acid;
Cinnamic acid;
total flavones;
volatile oil;
HPLC fingerprint
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize the best ingredients combination of Guizhi Gancao Decoction. Method The prescription was put into two groups, and extracting by semi-bionic extraction. The contents of Glycyrrhetinic acid, Cinnamic acid, total flavones, volatile oil and dry extract in the each extract were determined, and HPLC fingerprint of the refined by 50% ethanol was compared. Results Except the similar content of dry extract in two kinds of combinations, the other four index components in mixed extract is significantly higher than individual extraction. Two kinds of combinations extract fingerprints of the HPLC had no significant difference. HPLC gradients eluting total score area and main characteristic peak area in mixed extract were higher than individual extraction. Conclusion It is better that Guizhi Gancao Decoction extracted with Guizhi and Gancao mixed.
