Expression of DDR1a in colon carcinoma cells and its relationship with matrix metalloproteinase 2,9
- VernacularTitle:DDR1a在结肠癌细胞株中的表达及与基质金属蛋白酶2,9的关系
- Author:
Miao HE
- Publication Type:Journal Article
- Keywords:
Discoidin domain receptor tyrosine kinases1a;
Colon carcinoma cells;
Matrix metalloproteinase 2;
Matrix metalloproteinase 9
- From:
Journal of Chongqing Medical University
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the expression of DDR1a and the activities of MMP2,MMP9 in colon carcinoma cells and their mutual relations.Methods:The expression of DDR1a in colon carcinoma cell and human colon smooth muscle cell was detected by Western blot,the activities of MMP2,MMP9 were examined by gelatin zymography analysis.Results:The expression of DDR1a and the activities of MMP2,MMP9 in colon carcinoma cell(LOVO)which has stronger invasive behavior were significant higher(P
