Comparison between the methods for determing the entrapment efficiency of Nobiliside-A liposome
- VernacularTitle:Nobiliside-A脂质体包封率测定方法的研究
- Author:
Dan GUO
;
Yang XIONG
;
Peng SUN
;
Lili CUI
;
Jianming CHEN
- Publication Type:Journal Article
- Keywords:
Nobiliside-A liposome;
entrapment efficiency;
Sephadex G-50 column filtration method;
microcolumn centrifugation method
- From:
Chinese Traditional Patent Medicine
1992;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To establish a method for determing the entrapment efficiency(EE) of Nobiliside-A liposome. METHODS: Sephadex G-50 column filtration method and microcolumn centrifugation method were employed to separate the free drug and liposome. In order to select a better method to determine the entrapment efficiency of Nobiliside-A liposome. RESULTS: The two methods to determine the entrapment efficiency of the Nobiliside-A liposome got the similar results. CONCLUSION: In order to determine the entrapment efficiency of Nobiliside-A liposome conveniently and rapidly, we finally select microcolumn centrifugation method.
