Optimization on Extracting Technology of Baige Capsule by Orthogonal Design
- VernacularTitle:正交试验法优选复方白葛胶囊的提取工艺
- Author:
Yuntai CAO
;
Donglei SHI
;
Linmei PAN
- Publication Type:Journal Article
- Keywords:
Baige Capsule;
orthogonal design;
extraction process;
paeoniflorin
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To optimize an extracting technology for Fufang Baige capsule. Methods The orthogonal design was used for the inspection of water-extracting process and alcohol-precipitating process. Water volume, extracting time and extracting times were screened as inspection elements for water-extracting process. And liquid concentration, alcohol-precipitating concentration and incubating time were screened as inspection elements for alcohol-precipitating process. The transferring rate of paeoniflorin which is the indicator component in drug-Jun was screened as the inspection indicator for each fraction of extraction process. Results The optimal extraction conditions were as follows:for water- extracting process, that was extracting 2 times with 15-fold water, 2 hours for each time ; For alcohol-precipitating process, that was concentrating liquid to 1.0 g/mL Chinese herbs containing, then adding alcohol untill alcohol concentration ammouted to 70%, and at last putting it static for 18 hours. Conclusion The extracting technology was simple, economical and practical, and was able to increase production efficiency.
