Effect of Jiakang Formula on Thyroid Hormone and Thyroid Pathological Changes of Experimental Hyperthyroid Rats
- VernacularTitle:甲亢方对甲状腺功能亢进模型大鼠甲状腺激素和甲状腺病理变化的影响
- Author:
Fanglin HU
;
Xianju LIU
;
Fayin YI
- Publication Type:Journal Article
- Keywords:
hyperthyroicism;
Jiakang formula;
thyroid hormone;
thyroid;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Jiakang formula on thyroid hormone and thyroid pathological changes of experimental hyperthyroid rats. Methods Forty rats were given Euthyrox daily at 75 ?g/100 g ig and randomly divided into hyperthyroidism model group, control group, middle dose Jiakang formula group, high dose Jiakang formula group, each with 10 rats, as well as 10 rats as normal group. Three weeks later, the rats were killed for observing the effect of Jiakang formula on thyroid hormone and thyroid pathological changes of experimental hyperthyroid rats. Result Jiakang formula could lower the level of FT3, FT4, T3, T4 and promote the level of TSH, also improve thyroid pathological changes, especially in high dose Jiakang formula group. Conclusions Jiakang formula had the effect of improving the function and pathology of thyroid on experimental hyperthyroid rats.
