Observation of Effect of Nicardipine Combined with Metoprolol in the Treatment of Renal Hypertension
- VernacularTitle:尼卡地平联合美托洛尔治疗肾性高血压观察
- Author:
Xiaofeng HE
;
Wei LIU
- Publication Type:Journal Article
- Keywords:
Nicardipine;
Metoprolol succinate sustained-release tablet;
Renal hypertension
- From:
Chinese Journal of Pharmacoepidemiology
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the curative effect and security of nicardipine combined with metoprolol succinate sustained-release tablet on renal hypertension.Method:65 renal hypertension patients were randomly divided into two groups.The patients in the nicardipine group were treated with nicardipine 80 mg q8h,while the patients in the therapy group were treated with nicardipine 40mg qd and metoprolol succinate sustained-release tablet 47.5-95mg qd for 8 weeks.Their blood pressure,heart rate,hepatic function,renal function,blood glucose and lipid were observed and recorded before and after the treatment.Result:The total efficiency was 74.4%in the controlled group and 88.5%in the therapy group,respectively. There were no obvious changes or obvious adverse reactions in their heart rate,hepatic function,renal function,blood glucose and lipid after the treatment.Conclusion:Nicardipine combined with metoprolol succinate sustained-release tablet is efficient and safe but more efficient than nicardipine alone in the treatment of renal hypertension.
