The clinical analysis of 12 patients with thrombotic Microangiopathy
- VernacularTitle:血栓性微血管病12例临床分析
- Author:
Lin TANG
- Publication Type:Journal Article
- Keywords:
Thrombotic Microangiopathy;
Clinical studies;
Diagnosis
- From:
Journal of Chongqing Medical University
1987;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the clinical characteristics and treatment of thrombotic microangiopathy(TMA),to improve recognition of TMA.Method:Types,clinical and laboratory characteristics,treatment and prognoses of 12 patients with thrombotic microangiopathy admitted to our hospital between October 2004 and December 2007 were analyzed retrospective1y.Result:The clinical manifestations were characterized by microangiopathic hemolytic anemia(12/12),thrombocytopenia(12/12),elevated serum LDH value(12/12),and renal lesion(12/12),fever(5/12),and neurological abnormalities or mental disorders(7/12).3 patients were treated by plasma exchange therapy.1 patient fully recovered,4 patients took a turn for the better,and 7 patients died.Conclusion:TMA is a kind of severe acute syndrome with complicated pathenogenesis and high mortality.Management should depend on the type of TMA in order to improve curative efficacy and reduce mortality.
