Effects of Degraded and Natural Polysaccharides from Porphyra Haitanensis on Proliferation of Lymphocytes
- VernacularTitle:坛紫菜多糖及其降解产品对免疫细胞增殖的影响
- Author:
Tingting ZHAO
;
Quanbin ZHANG
;
Zhien LI
;
Zuhong XU
- Publication Type:Journal Article
- Keywords:
Porphyra haitanensis;
Polysaccharides;
T-lymphocytes;
B-lymphocytes
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the property of natural polysaccharides(P) from Porphyra haitanensis T. J. Chang et B. F. Zheng and its degraded polysaccharides(P3),and to investigate their effects on proliferation of lymphocytes. Methods P3 and P were identified by IR spectra. Their effects on immunological function were studied by cell culture technique. Results P3 and P displayed significant effects on promoting the proliferation of T-lymphocytes,and had inhibitory effects on the proliferation of B-lymphocytes in a dose-dependent manner. The effects of P3 were more powerful than P. Conclusion The degraded and natural polysaccharides from Porphyra haitanensis(P3 and P) can regulate the proliferation of lymphocytes,which may be related to their molecular weights.