Study on Epidemiological Characteristics study of Adverse Reaction Induced by Chinese Medicine Injection Based on Database Establishment and Analysis
- VernacularTitle:基于数据库分析的中药注射剂不良反应流行病学特点研究
- Author:
Jiarui WU
;
Bing ZHANG
- Publication Type:Journal Article
- Keywords:
Chinese medicine injection;
Adverse reaction;
Database
- From:
Traditional Chinese Drug Research & Clinical Pharmacology
1993;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiological characteristics of adverse reaction induced by Chinese medicine injection. Methods Domestic medicinal periodicals issued from the year 1972 to 2007 were searched,and 2 333 adverse reaction(ADR) cases were analyzed by database establishment and statistic method. Results 2 333 ADR cases involving 82 different kinds of Chinese medicine injection were collected and 422 cases were related to Shuanghuanglian Injection. Chinese medicine injection induced multiple systematic ADRs. The incidence of skin lesion(598,21.06 % )and that of anaphylactic shock(580,20.43 % )dominated in ADRs. The incidence of ADR was 54.05 % in the male and 45.95 % in the female. Average age of patients was(40.67? 21.45)years old. Fifty-one patients(2.19 % )died of severe ADRs. Conclusion Chinese medicine injection should be used with more rationality and enhance prevention awareness to reduce the occurrence of ADR.
