Formula Screening and Optimizing for the Dispersible Tablets of Breviscapinum
- VernacularTitle:灯盏花素分散片的处方及工艺研究
- Author:
Qi SONG
;
Minwei FAN
;
Bing WANG
- Publication Type:Journal Article
- Keywords:
breviscapinum dispersible tablets;
dispersible uniformity;
rigidity;
disintegration time;
scutellarin
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish a suitable formulation for the dispersible tablets of breviscapinum. Methods The preparative process was scanned out by single factor test and orthogonal design. A comprehensive scoring analysis was performed with disintegrating time and rigidity as the indexes. Results The demonstration for the dispersible tablets from the optimized formulation,being totally disintegrated within three minutes and sifted through the sieve in size of the 2nd,show better dissolubility in-vitro in comparison with the common tablets and their quality meets with the requirement for the dispersible in Phamarcopoeia of the People's Republic of China. Conclusion The formulation screened out for the dispersible tablets of breviscapinum is suitable for the production on a large scale.
