Dynamic observation on the intraperitoneal glucose tolerance test in the non-hyperglycemic rats treated with streptozotocin
- VernacularTitle:链脲佐菌素未致高血糖大鼠腹腔葡萄糖耐量试验的动态观察
- Author:
Xiaohong WEN
- Publication Type:Journal Article
- Keywords:
Rats;
Diabetic mellitus;
Streptozotocin;
Blood glucose;
Intraperitoneal glucose tolerance test
- From:
Journal of Chongqing Medical University
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study whether the glucose tolerance was impaired in the non-hyperglycemic rats treated with strepto-zotocin(STZ).Methods:Male SD rats,aged 10￣12 weeks,were divided into two groups:experimental group,with an intraperitoneal injection of 30 mg/kg(low dose)or 60 mg/kg(high dose)STZ;control group,with injection of equal dose acidified saline.1￣12 weeks after injection,the intraperitoneal glucose tolerance tes(tIPGTT)was performed in the non-hyperglycemic rats(fasting blood glucose
