The expressions of ICAM-1 and VCAM-1 in HIE neonatal rabbits
- VernacularTitle:ICAM-1及VCAM-1等在HIE新生兔的表达
- Author:
Jingcang LIN
- Publication Type:Journal Article
- Keywords:
The intranterine anoxemia;
Neonatal rabbits;
Conglutinated molecule;
CD11b/CD18;
Intercellular adhesion moleacule-1(ICAM-1);
Vascular cell adhension moleules 1(VCAM-1)
- From:
Journal of Chongqing Medical University
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:Searching after the effects of the expressions the neonatal rabbits with chronic intrauterine anoxemia give to neutrophil and conglutinated molecule.Method:Choosing 15 Zelanian rabbits that have been in afternoon pregnancy,we divide them into three stochastic contratest groups by chance:the control group,the anoxic group and the group interfered with Chinese traditional medicine.Then,we contrast the expressions and changes of these groups with CD11b/CD18,ICAM-1 and VCAM-1.Results:Contrasting the CD11b/CD18,ICAM-1 and VCAM-1 of the anoxic group and the group interfered with Chinese traditional medicine with chinese traditional medicine with the control group,we have found their expressions all more remarkably strengthened;There is some difference in expression between the anoxic group and the group interfered with Chinese traditional medicine,but it has little statistical significance.Conclusion:In this article,there occurs the mention:the chemotaxis of neutrophil has been strengthened and the endotheliocytosis of cerebrovascular has been conglutinated under anoxemia;as a result,the chemotaxis and endotheliocytosis have marred the brain cell tissue and participated in whole pathological and physiological process.
