The effect of NRP-1 on priliferation,invasion and tumor angiogenesis of human laryngocarcinoma cell line Hep-2
- VernacularTitle:NRP-1对喉癌Hep-2细胞增殖侵袭及体外癌细胞促血管形成的影响
- Author:
Yu GONG
- Publication Type:Journal Article
- Keywords:
Laryngeal carcinoma;
Neuropilin-1;
Tumorigenesis;
Angiogenesis.
- From:
Journal of Chongqing Medical University
2007;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
objective:To identify the function of NRP-1 in progression and angiogenesis of laryngocarcinoma cell line Hep-2 in vitro.methods:MTT,the cell migrate,attack and vascular formation experiments in vitro was used to evaluate the effect of NRP-1 antigen on the migrate,attack and angiogenesis capability of laryngocarcinoma cell line Hep-2.Results:The proliferation inhibition ratio of Hep-2 cells was risen up as the NRP-1 antigen's concentration was increaced(r=0.624,P
