Preparation and stability test of Lyophiled Royal Jelly Soft Capsule
- VernacularTitle:冻干蜂王浆软胶囊的制备及稳定性影响因素研究
- Author:
Jian HE
;
Tao PENG
;
Meiling DAI
;
Zheng JIANG
;
Chunhui LIU
- Publication Type:Journal Article
- Keywords:
Royal Jelly;
Soft Capsule;
Formulation process;
stability test;
10-HDA;
HPLC
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To prepare the Lyophiled Royal Jelly Soft Capsule and study its stability and Influential factors.METHODS:The suspending agent and processing method were optimized using sedimentation volume rate as the index.Soft capsules were prepared and product stability under high temperature and high humidity environment was studied according to the determination of the content of 10-HAD by HPLC.RESULTS:The finished product yield in pilot test was more than 90%,the soft capsule products stored in cold were stable,while those stored under room temperature or high temperature and high humidity were unstable with a noticeable decrease in quality.Water content in capsule shell affects the 10-HDA content of the finished product.CONCLUSION:The preparative process is feasible and the products should be storaged in cold enviroment.
