Evaluation on normalized HPLC fingerprints of Shegan Antiviral Injection
- VernacularTitle:射干抗病毒注射液统一化HPLC指纹图谱的评估
- Author:
Guoxiang SUN
;
Yang SONG
;
Yueshan HU
;
Kaishun BI
- Publication Type:Journal Article
- Keywords:
Shegan Antiviral Injection;
normalized chromatographic fingerprints;
chromatographic fingerprint index at fixed point F_(a/t),chromatographic fingerprint equal signal index F_(t/a) .
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To establish the normalized chromatographic fingerprints(NCFP) of Shegan Antiviral Injectionl(Rhizoma Belamcandae,Flos Lonicerae japonicae,Herba Artemisiae scopariae,Radix Bupleuri,etc.)(SGKBDI) and to evaluate them by using the 25 relatively normalized parameters.METHODS:The chromatographic fingerprints of the eight herbal drugs,two intermediates and preparation of SGI were determined by RP-HPLC.The 11 chromatographic fingerprints were evaluated by 25 relatively normalized index calculated by the software of Digitalized Evaluation System of Super-information Characteristic for Traditional Chinese Medicine Fingerprints 3.0.RESULTS:The best fingerprints were S4 Herba Artemislae Scopariae and S7 Radix Isatidis,the next were S2 Flos Lonicerae、 S5 Radix Bupleuri、 S6 Herba Taraxaci、 S8 Folium Isatidis,S10 intermediat Ⅱ and S11 Sgkbdi.CONCLUSION:The 25 characteristic parameters can be used to objectively,authentically and thoroughly reveal the separation of chromatographic fingerprints and its normalized characteristics of the NCFP of SGKBDI.
