Toxicological study on Jiutong Capsule
- VernacularTitle:九通胶囊的毒理学实验研究
- Author:
Wei CHEN
;
Xianrong SHEN
;
Dingwen JIANG
;
Fuxing JIA
;
Zhiyong CHU
- Publication Type:Journal Article
- Keywords:
Jiutong Capsule;
acute toxicity;
heredity toxicity;
mouse
- From:
Chinese Traditional Patent Medicine
1992;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To estimate the toxicological characterization of Jiutong Capsule(Radix Puerariae lobatae,Fructus seu Semen Hoveniae,etc.).METHODS:The acute toxicity test,micronucleus test of bone marrow cell,sperm shape abnormality test in mice,the Ames test,and 30 days feeding test in rat were performed.RESULTS:(1) The acute toxicity test showed that LD_ 50 of Jiutong Capsule was more than 10.0 g/kg.(2) The result of Ames test,micronucleus test of bone marrow cell,and sperm shape abnormality test were negative.(3) The 30 days feeding test showed that Jiutong Capsule had no cumulate toxicity in mice.CONCLUSION:The results show that Jiutong Capsule does not have toxicity,and it can't cause mutation and heredity toxicity.
