Protective Effects of ?-asarone against Myocardial Ischemia/Reperfusion Injury in Cultured Cardiac Myocytes
- VernacularTitle:?-细辛醚对缺血/再灌注损伤心肌细胞的保护作用
- Author:
Qiwen WANG
;
Qiduan WU
;
Yizhi CHEN
- Publication Type:Journal Article
- Keywords:
?-asarone;
cardiac myocytes;
ischemia/reperfusion;
Na2S2O4
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the protective effects of ?-asarone against the myocardial ischemia/ reperfusion injury (MI/RI) in cultured cardiac myocytes. Methods MI/RI model was set up with Na2S2O4, which make use of rat cardiac myocytes. The viability of cardiac myocytes (using MTT method), dehydrogenase (LDH, CK) activitices in the medium were measured. Results In MI/RI model, ?-asarone can obviously advance the viability of cardiac myocytes, and decrease the dehydrogenase (LDH, CK) activitices in the medium. Conclusion ?-asarone showed protective effects against the myocardial ischemia/reperfusion injury in cultured cardiac myocytes.
