Influence of Removing Dampness,Melting Phlegm and Tonifying Spleen Method on Nitric Oxide Synthase and Gene Expression of Vascular Endothelial in Hyperlipidemia Rats
- VernacularTitle:利湿化痰健脾法对高脂血症大鼠一氧化氮合酶、血管内皮素基因表达的影响
- Author:
Yiping GONG
;
Shaoling ZHOU
;
Junjie ZHANG
- Publication Type:Journal Article
- Keywords:
law of removing dampness, melting phlegm and tonifying spleen;
hyperlipidemia rats;
NOS;
vascular endothelial gene
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the law of removing dampness, melting phlegm and tonifying spleen on blood lipids in hyperlipidemia rat and its vascular endothelial protective effect. Methods Animals were randomly divided into 6 groups, the high-fat diet of 35 d, 16 d orbital check blood lipids to confirm modeling success and gavage was given by different experimental requirements. NOS and vascular endothelial gene expression were determined at 3rd and 7th day. Results After treatment, NOS expression in experimental rats compared with the normal group, P