Effect of Jiawei Xiaochengqi Decoction on Intestinal Endotoxemia of Chronic Hepatic Injury Rats
- VernacularTitle:加味小承气汤对慢性肝损伤大鼠肠源性内毒素血症的影响
- Author:
Lianyin GAO
;
Xiuwen FU
;
Yong TAN
- Publication Type:Journal Article
- Keywords:
Jiawei Xiaochengqi Decoction;
chronic hepatic injury;
endotoxemia;
rat
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the therapeutic effect and mechanism of Jiawei Xiaochengqi Decoction on hepatic injures by endotoxin in rats. Methods Endotoxemia model of Wistar rats was made by thioacetamide. Blood biochemistry and pathological changes were examined to observe the effect of Jiawei Xiaochengqi decoction on liver function, TNF-?, endotoxin of the model rats. Results Jiawei Xiaochengqi Decoction could reduce the contents of TNF-?, endotoxin in the blood and the degree of hepatic cells necrosis of Wistar rats. There was significant difference compared with model group (P
