Preliminary Study on Apotosis of PG Cells Induced by Herba Hedyotis Diffusae
- VernacularTitle:白花蛇舌草诱导人肺巨细胞癌细胞株PG细胞凋亡的初步研究
- Author:
Jie LI
;
Daizhou ZHANG
;
Meifang MA
- Publication Type:Journal Article
- Keywords:
Herba Hedyotis Diffusae;
PG cell;
apoptosis;
drug containing serum
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the anticancer mechanism of Herba Hedyotis Diffusae on PG cell by observing the action of Herba Hedyotis Diffusae in inducing apoptosis of PG cells. Method After treating PG cells with different doses of drug containing serum of Herba Hedyotis Diffusae, FCM was used to detect the apoptosis of PG cell. Result After treating PG cell with Herba Hedyotis Diffusae, typical apoptosis characteristics could be seen and apoptosis rates were increased with the relation of dosage-effect, which were 6.86%, 9.77% and 11.69%, respectively. Conclusion Inducing the apoptosis of tumor cells maybe part of the anti-tumor mechanism of Herba Hedyotis Diffusae.
